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Scientific Review Protocol Protocol v33.48.0 · Active 2026

Editorial & Scientific Review Policy

PureSuppHub Editorial & Scientific Review Policy — Learn about our independent dietary supplement research methodology, evidence hierarchy, PubMed citation integrity, and FTC/FDA compliance.

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1. Purpose & Editorial Independence

PureSuppHub Journal operates as an independent supplement formula research, label audit, and educational review desk. Our primary mission is to empower consumers with factual, evidence-grounded insights regarding dietary supplement formulations, botanical bioavailability, and physiological mechanism pathways.

We maintain strict editorial independence. Supplement manufacturers, laboratory brand owners, distributors, and marketing agencies do not dictate, influence, preview, or censor our monograph analyses, dosage threshold critiques, or comparative evaluations. All evaluations are conducted autonomously by our research team.

2. Scientific Evidence Hierarchy

Our literature synthesis relies on publicly accessible, peer-reviewed biomedical research indexed in the National Library of Medicine (PubMed/MEDLINE), Cochrane Library, European Medicines Agency (EMA), and established national pharmacopeias. Our analysis applies a tiered evidence hierarchy:

  • Tier 1 — Gold Standard Human Evidence: Double-blind, randomized, placebo-controlled human clinical trials (RCTs), systematic reviews, and meta-analyses.
  • Tier 2 — Established Pharmacognosy Monographies: Authoritative botanical monographs from the World Health Organization (WHO), European Scientific Cooperative on Phytotherapy (ESCOP), and the German Commission E.
  • Tier 3 — Preliminary Mechanistic Investigations: In vitro enzymatic assays, receptor-binding studies, and animal pharmacological models (always explicitly contextualized as preliminary non-human data).

3. Authorship & Research Desk Governance

Articles and botanical monographs are curated and published collectively by the PureSuppHub Independent Research Desk. Our team comprises scientific researchers specializing in nutritional biochemistry, phytochemistry analysis, and comparative formulation benchmarking.

Non-Clinical Practice Notice: PureSuppHub does not operate a private medical practice, clinic, or telehealth service. The information provided across this journal is intended solely for educational, research, and consumer discernment purposes. It does not replace individualized diagnostic assessment or clinical prescription from a licensed healthcare practitioner.

4. Scholarly Fair Use Citation Protocol

All scientific assertions and clinical trial references cite original authors, journal titles, digital object identifiers (DOIs), and PubMed identifiers (PMIDs) under the international doctrine of Fair Use.

Non-Endorsement Notice: The citation of published academic literature does not represent an endorsement, sponsorship, or commercial partnership between the cited researchers/universities and PureSuppHub or any commercial dietary supplement analyzed.

5. Commercial Transparency & FTC Compliance (16 CFR Part 255)

In compliance with Federal Trade Commission (FTC) guidelines, we maintain full disclosure of our commercial referral structure. When readers choose to access official manufacturer portals via direct links on our platform, PureSuppHub may receive a referral commission at zero additional cost to the customer. This revenue supports our independent research operations and computational infrastructure without compromising our objective dosage critique.

6. Mandatory FDA Statutory Notice (DSHEA 1994)

The statements made regarding dietary supplements on this website have not been evaluated by the Food and Drug Administration. Dietary supplements are regulated under the Dietary Supplement Health and Education Act of 1994 (DSHEA) and are not intended to diagnose, treat, cure, or prevent any disease. Always speak with your doctor before initiating any new supplement protocol.

7. Fact-Checking & 48-Hour Correction Protocol

We are committed to factual accuracy and scientific rigor. If you identify a formula reformulation, updated PubMed trial result, or dosage ambiguity in our monographs, please submit documentation to our editorial team at puresupphub@gmail.com with the subject line "Editorial Correction Request". Verifiable corrections are investigated and updated within 48 business hours.